Abstract: The paper discusses the impact of Christianity on the institutions of divine kingship and chiefship among the Asante people of Ghana during the late pre-colonial and colonial periods. The thrust of the paper is that separate categories of religion and politics emerged in Asante society as the colonial administration sought to facilitate missionary work and conversion while at the same time they supported the chiefs as the secular rulers of the country. The analysis is based on Dumont’s ideas on the differentiation of the political category and the characteristics of the modern state. Dumont’s own work on secularization focused on long-term historical developments that were markedly different from the abrupt changes described here. Nevertheless, his ideas help us significantly in comprehending the profoundness and radicality of this transformation. Additionally, the aim of the paper is to provide some historical background for understanding debates about the nature and value of traditional chieftaincy in present-day Ghana.